Many of the body's processes slow down or falter as we get older, including tissue regeneration. In a new study, researchers ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

The nucleolus serves as the central hub for ribosomal DNA (rDNA) transcription and ribosome biogenesis, processes essential for protein synthesis and cellular proliferation. rDNA transcription is ...

Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.

Delivery of therapeutic proteins or other intracellular materials has been a long-standing challenge for translational medical researchers. Effective strategies can present a powerful tool for many ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...